Mammary Carcinoma in a Male Cat: A Diagnosis Worth Not Missing
Male cats can develop mammary carcinoma. The diagnosis should be on the differential list for any mammary region mass in a male cat, regardless of neuter status. Given that the vast majority of feline mammary tumors are malignant, histopathology is not optional — cytology alone is unreliable for distinguishing benign from malignant mammary lesions in cats.
Feline Injection-Site Sarcoma: Revisiting Pathogenesis in the Light of Current Evidence
And yet, more than three decades later, the pathogenesis of FISS remains incompletely understood. The broad strokes are established: chronic local inflammation at an injection site appears to trigger malignant transformation of fibroblasts or myofibroblasts in genetically susceptible cats. But the molecular details — what drives that transformation, why only certain cats develop it, and which specific pathways sustain tumor growth — are still being worked out.
NGS in Veterinary Oncology: What's Commercially Available Now and Where It's Headed
…next-generation sequencing (NGS) has arrived in veterinary medicine, but it remains in early clinical adoption, the available assays are almost exclusively validated for dogs, and these tools work best as an adjunct to histopathology rather than a replacement for it. This post offers an honest overview of where things stand today — what you can actually order, what the evidence shows, and where the field is likely headed.
Why Skin Punch Biopsies Come Back “Non-Diagnostic” — And How to Improve Your Diagnostic Yield
Inflammatory and early neoplastic processes can be patchy.
Submitting a single punch biopsy for generalized dermatologic disease significantly reduces diagnostic confidence.